ROUSES POINT, N.Y. — New York lost nearly 14,000 private sector jobs in October, but the seasonally adjusted unemployment rate in New York City and across the state dipped slightly to 5.7 percent.

That's a drop from 5.8 percent in September, but up from 4.6 percent in October 2007. Outside New York City, St. Lawrence County had the highest unemployment rate last month at 6.9 percent. Nationally, the rate was 6.5 percent in October.

The latest numbers were released by the state Labor Department on Thursday, a day after HSBC Mortgage Corp. said it was cutting 225 jobs at its Buffalo-area headquarters.

Since October 2007, the largest losses have been 17,400 jobs in manufacturing and 16,500 in the financial industry, followed by 11,000 in trade, transportation and utilities, according to state data covering both the public and private sectors. Jobs in education and health services grew over that time by 30,200 and 11,200 more workers were employed in government. The total of private sector jobs dropped 14,100 from 7,254,000 to 7,239,900 over the year.

Gov. David Paterson said in late October that jobs lost to turmoil on Wall Street would eventually top 45,000. Rod Fortran, a labor department analyst, said Thursday there are more cuts to come in the financial sector that aren't reflected in the latest employment numbers.

While job cuts have been concentrated around New York City and western New York, the effects of the state's economic slowdown have been far reaching. One of the North Country's biggest private employers — Wyeth Pharmaceuticals — announced plans this week to lay off 118 of the 725 remaining workers at its plant in Rouses Point.

"It's just a sign of the times," said George Rivers, mayor of the village on the Canadian border, who noted that about 1,200 people worked at the plant two years ago. "But it's not so bad compared to what's happening around the country. They're laying off thousands in the banking industry."

The Wyeth plant — a sprawling, tightly guarded industrial complex — is just a few blocks from the main street, where some business owners are worried about its shrinking work force.

"There's been nobody around," said Binnie Munnik, who stopped Thursday for a coffee at a cafe a few doors down from the antique shop she has run since 1993.

Beefed up border patrol budgets in recent years have brought some new people to the area, but Munnik said she's still having trouble finding a buyer for her lake front house.

"I've had it up for sale for years," she said.

Just last August, North Country business boosters and government officials were celebrating the salvation of the plant, which Wyeth had planned to close but recently sold to Akrimax Manufacturing, a privately owned pharmaceutical company based in New Jersey.

Wyeth is shifting its manufacturing out of the plant, and Akrimax plans to fully take over by the end of next year. The company said it plans to bring additional business to the plant through contract manufacturing agreements with other drug makers but hasn't provided specific projections.

"It's disappointing, but it's only temporary," Plattsburgh-North Country Chamber of Commerce president Garry Douglas said of the job losses.

Douglas said some of the area's small businesses likely have cut jobs, but so far none of the North Country's major employers aside from Wyeth have done so. He also pointed to some developments — including a bus manufacturer's plan to build an assembly plant expected to employ about 300 people in Plattsburgh by 2011 — as reasons to be optimistic.

Like Douglas, coffee shop owner Kris Duus remains upbeat even as several shops and buildings along Rouses Point's small main strip sit vacant. Locals and the additional border patrol staff make up most of her shop's business, she said.

"It's a very walkable downtown, and that helps," said Duus, who opened the shop a little over a year ago.

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