Press-Republican

FYI...

November 12, 2013

A new reason why newborns can't fight colds

One of newborns' biggest vulnerabilities is largely invisible: In the weeks after birth, babies are especially susceptible to infection because their immune systems aren't fully functional. There are a handful of theories to explain this liability, and now a research team has added a new one to the list: Immune suppression in early life might help prevent inflammation in the infants' intestines as they become colonized by the helpful bacteria they need to stay healthy.

Newborns are more likely than older babies to catch, and die from, serious infections. The reason is fuzzy - indeed, there may be more than one explanation. One theory is that much like their brains, their lungs, and the rest of their bodies, infants' immune systems just haven't fully matured yet. Another is that both mothers-to-be and their in utero companions have suppressed immune systems, so that neither rejects the other. After birth, the thinking goes, it takes babies a month or so to boost their immunity.

Seeking new ways to better understand this process, Sing Sing Way, a pediatric infectious disease doctor at Cincinnati Children's Hospital Medical Center, wondered whether transferring immune cells from adults might rev up their immune systems. Yet when he and his colleagues injected infection-fighting cells from the spleens of adult mice into 6-day-old pups, nothing happened: The pups were just as vulnerable to harmful bacteria as control animals. Probing more deeply into this surprise, they found that the injected cells simply stopped functioning in the newborn animals. Then Way's group did the reverse transplant - they gave adult mice newborn immune cells that were inactivated in the pups and found that they "turned on" in the mature animals. These experiments "told us it wasn't a problem with the neonatal cells themselves," Way says. Rather, he believes, the environment - either a newborn body, or an adult one - guided how the cells behaved.

Text Only | Photo Reprints
FYI...
  • mama.jpg What we get wrong about millennials living at home

    If the media is to be believed, America is facing a major crisis. "Kids," some age 25, 26, or even 30 years old, are living out of their childhood bedrooms and basements at alarmingly high numbers. The hand-wringing overlooks one problem: It's all overblown.

    July 29, 2014 1 Photo

  • Your chocolate addiction is only going to get more expensive

    For nearly two years, cocoa prices have been on the rise. Finally, that's affecting the price you pay for a bar of chocolate - and there's reason to believe it's only the beginning.

    July 28, 2014

  • Facebook tests button to let people shop from its website

    Members on desktop computers or mobile devices can click a "buy" button to make purchases through advertisements or other posts on the world's largest social network, the Menlo Park, California-based company said Thursday in a blog post.

    July 27, 2014

  • Wal-Mart to cut prices more aggressively in back-to-school push

    Wal-Mart Stores plans to cut prices more aggressively during this year's back-to-school season and will add inventory to its online store as the chain battles retailers for student spending.

    July 26, 2014

  • An oncologist uses scorpion venom to locate cancer cells

    Olson, a pediatric oncologist and research scientist in Seattle, has developed a compound he calls Tumor Paint. When injected into a cancer patient, it seems to light up all the malignant cells so surgeons can easily locate and excise them.

    July 25, 2014

  • An alternative diagnosis to ADHD: Schoolchildren need more time to move

    The Centers for Disease Control and Prevention tells us that in recent years, there has been a jump in the percentage of young people diagnosed with attention deficit and hyperactivity disorder, commonly known as ADHD: 7.8 percent in 2003 to 9.5 percent in 2007 to 11 percent in 2011.

    July 24, 2014

  • Hospitals let patients schedule ER visits

    Three times within a week, 34-year-old Michael Granillo went to the emergency room at Northridge Hospital Medical Center in Los Angeles because of intense back pain. Each time, Granillo, who didn't have insurance, stayed for less than an hour before leaving without being seen by a doctor.

    July 23, 2014

  • Why it's basically impossible to delete those naked selfies you text

    If you're selling an old Android smartphone on an online auction site, you could be giving away rather more than you intend to, according to a recent investigation by anti-malware company Avast.

    July 21, 2014

  • Why does the Vatican need a bank?

    The Vatican Bank's history reads more like Dan Brown than the financial pages, but its worst -- and weirdest -- days may be behind it.

    July 18, 2014

  • Almost half of the world actually prefers instant coffee

    Americans' taste in coffee might be getting more high-end _with a growing fixation on perfectly roasted beans, pricier caffeinated concoctions, and artisan coffee brewers - but it turns out a surprisingly big part of the world is going in the opposite direction: toward instant coffee.

    July 17, 2014